If voting against Pete Buttigieg is homophobic, what about voting against Richard Grenell?

Pete Buttgieg and Richard Grenell

On February 2, the Senate approved Pete Buttigieg for the Cabinet position of Secretary of Transportation. The final vote was 86-13, with one senator not voting. All 13 nay votes were Republicans, which resulted in cries of homophobia from some people. Is voting against a nomination all it takes for